Minneapolis, MN (Sports Network) – Tarvaris Jackson took over for an injured Brett Favre early in the first quarter and threw for 187 yards and two touchdowns, as the Minnesota Vikings routed the Buffalo Bills, 38-14, at the Metrodome.
Favre suffered a shoulder injury when he was hit from behind by Arthur Moats on his first passing attempt - an interception by Drayton Florence. The 41 year old, who started his 297th consecutive regular-season game, was helped to the sidelines and did not return. Jackson completed 15-of-22 passes, but threw three interceptions.
Adrian Peterson, who was questionable with an ankle injury, rushed for 107 yards and three touchdowns for the Vikings (5-7), who earned a 17-13 victory at Washington last week in interim head coach Leslie Frazier’s debut. Minnesota has won three of its last five. Sidney Rice caught five passes for 105 yards and two scores in the victory.
Ryan Fitzpatrick threw for 158 yards on 15-of-25 efficiency with one touchdown and one interception for Buffalo (2-10), which dropped a 19-16 overtime decision to Pittsburgh last weekend and has split its last four games. Florence had two interceptions — one returned for a 40-yard touchdown — and David Nelson had a 12-yard TD reception in defeat.