The game centered around Griffin and Minnesota's Kevin Love -- the NBA's top two double-double generators. Love tallied 18 points and 18 boards to secure his franchise-record 42nd consecutive double-double, and 51st of the season. Griffin has 46.
Randy Foye finished with 21 points and six assists for the Clippers, who improved to 2-6 on an 11-game road trip. Ryan Gomes chipped in 18 points.
Los Angeles holds a 21-35 record heading into the All-Star break.
Wayne Ellington made five three-pointers en route to 18 points off the bench for the Timberwolves, who have dropped four straight and 13 of their last 16 overall. They head into the break with a dismal 13-43 mark.
The Clippers led by as many as eight in the first quarter and held a 23-20 edge after 12 minutes.
Minnesota outscored Los Angeles, 22-20, in the second stanza to cut its deficit to 43-42 at the break.
Holding a 49-48 lead early in the third, the Clippers ripped off six straight points. Baron Davis' three-pointer made it 55-48 with nine minutes remaining.
LA went on a 9-0 run moments later to create some distance. Foye tallied the first five points of the surge, which Griffin capped with a jumper and a slam for a 66-52 lead.
It was a 72-62 contest heading to the fourth, and the Timberwolves never got closer than six the rest of the way.
The Clippers won three of the four meetings this season...Los Angeles shot 45.6 percent from the field, while Minnesota made 35.4 percent of its shots.